With most of my "utility" cutting where I am making something out of some scrap left-overs, I just move the bit over the center of the clear area and hit Z2. I dont have to be exactly in the center, anywhere close will work, as the last cut frees the part from the stock and will never know how close it came to some other holes from previous projects.
Z0 is critical, and the ZZero needs to be reset anytime you change bit or material.
Beyond that its pretty easy, much to learn of course!
Hope that helps-
D
"The best thing about building something new is either you succeed or learn something. Its a win-win situation."
--Greg Westbrook