The first "sandwich " sign I made was a learning experience and cost me a bit ! But like they say "a good education is never free".
I made a double sided HDU sign using 2 1.5" sheets of precision board . Between these I put a MDO spine in and joined it all together with 6 beads of Gorilla glue.
I placed plywood accross sawhorses and put the sign on top. Then another sheet of .5" plywood. On top of this I put 8 1 gallon cans of paint to keep it together.
When I got back the next day everything looked great !
I put a vinyl frame kit together and readied the sign for delivery.
The glue in the center had never set up completely. When I came back from luch the Gorilla glue had THEN expanded and ooozed out between the sign and the vinyl frame. IT MADE ONE HECKUVA MESS !
Looked like the sign had an afro !
I saved the sign but had to replace the vinyl sign frame. I actually ended up making a frame from 4x4s.
Now ,when I use Gorilla glue I make a pass with the bot about .250" deep . I do this every 6 inches. Then put the gorilla glue in the slots. It allows it to get some air and set up better. If you do have over expansion , you can just lop it off with a pocket knife.
Others may have more ideas, but this has worked well for me in this application.