A few thoughts based on my two machines.
Both 4g std machines.
I was having trouble with the new sb3 for a while when it was buggy. (3.6.5) time frame.
They sent me a newer v204 interface card for my controller.
I had tons of trouble with lost comm. I did the hub, usb card, several calls to tech support. Finally after the bugs were out of the sb3(version 11) I put my old card back in and have not had trouble any more.
My prs 4g also has that old board now and still no trouble.
I did have some trouble getting the ecab link running and a lot of that was due to not enough ram on the pc to the bot. It was loosing com during the link running.
I put 2 gigs in it and those troubles went away. (Thanks to Gary)
I would think on an alpha with newer controllers, Ram would be critical as well. Folks running those machines can give you more insight to the pc's that work on em. If I were going alpha, I would be looking for at least 4 gigs of ram on my pc for the machine.
If your machine is trying to run faster than your pc will allow, I think you will loose comm.
Kenneth